WARNING: USE IN PREGNANCY
When pregnancy is detected, discontinue AVAPRO or AVALIDE as soon as possible. When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. [See
Warnings and Precautions: Fetal/Neonatal Morbidity and Mortality in the
full Prescribing Information.]